RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
SNHG7
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
q-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
DVL2
Pathway
WNT SIGNALING PATHWAY; CATENIN BETA 1
PubMed ID
Title
Loss of lncRNA-SNHG7 Promotes the Suppression of Hepatic Stellate Cell Activation via miR-378a-3p and DVL2
Year
2019
Function
"We demonstrate that snhg7 reduces mir-378a-3p and attenuates its control on dvl2, leading to aberrant wnt;beta-Catenin activity, which contributes to liver fibrosis progression."